MONTREAL, QC
Advances and Innovations in Integrated and Translational Toxicology
December 3 – 5, 2023
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Albert Licollari, DVM, PhD, DABT
Nucro-Technics
Chair, 2023 Programme Committee
We are pleased to announce that the 55th Annual Symposium will be held by the STC in Montreal, QC from December 3-5, 2023. The symposium’s theme will revolve around the latest advancements and innovations in Integrated and Translational Toxicology. The event will feature a wide range of informative lectures, from cutting-edge research to regulatory insights and health impacts. This year, the symposium will focus on emerging toxicology topics like artificial intelligence and machine-learning tools, microphysiological models, safety biomarkers, and predictions, as well as food chemical safety. We are excited to have world-class experts share their knowledge and expertise with attendees.
Dr Hartung will be discussing research topics ranging from “Toxicity Testing for the 21st Century” to the “Human Exposome Project”.
In addition, distinguished speakers from academia, industry and government will bring lates topics driving toxicology research today in the areas of artificial intelligence and machine-learning tools, microphysiological models, safety biomarkers and toxicology outcome predictions, as well as food chemical safety.
SCIENTIFIC PROGRAM 
DAY 1 – December 3
STC Board of Directors Meeting
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ICT-2028 Vancouver 1st Planning Meeting
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Meet & Greet @ Featured Montreal Restaurant
DAY 2 – December 4
[ 8:15 – 8:30 am ]
Welcome and Opening Remarks
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[ 8:30-9:00 am ]
SESSION I
Artificial intelligence/machine learning in Predictive Toxicology
Chair – Albert Licollari, Director of Toxicology, Nucro-Technics
8:30 – 9:00 > Standardized Informatics for Regulatory and Safety Assessments
Andy Nong, ScitoVation, LLC, Director of Computational Toxicology
9:00 – 9:30 > To AI or Not: Nitrosamine Potency Prediction Defined
Kevin Cross, PhD, Vice President, Principal Investigator U.S. FDA Collaborations, Instem
9:30 – 10:00 > Estimating steady-state blood concentrations (CSS) and Administered Equivalent Doses (AEDs) from cellular (in vitro) bioassays using toxicokinetic models
Alessandro Sangion, PhD, Arnot Research and Consulting
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10:00 – 10:30 > Coffee/Tea Break
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[ 10:30 – 11:30 am ]
Plenary Lecture
From Toxicity Testing for the 21st Century to a Human Exposome Project
Thomas Hartung, PhD, Center for Alternatives to Animal Testing (The Johns Hopkins University Bloomberg School of Public Health)
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[ 11:30 – 12:00 am ]
Flash talk
Poster award finalists
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[ 12:00 am – 1:00 pm ]
Lunch break
Lunch and Poster (viewing and judging)
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[ 1:00 – 2:55 pm ]
SESSION II
Microphysiological Systems for Toxicological Safety Prediction and Regulatory Challenges
Chair – Margaret Magdesian, PhD, Ananda Devices | Co-chair – TBD
1:00-1:30 > Development of Predictive Drug Discovery Platforms Merging Human Tissue Chips and Translational Software
Murat Cirit, PhD, CEO, Javelin Biotech
1:30-2:00 > 3D models and Toxicology Applications
Jan Lichtenberg, PhD, CEO, InSphero
2:00-2:30 > Organ-on-a-chip models for disease modelling and drug testing
Milica Radisic, PhD, Canada Research Chair in Organ-on-a-Chip Engineering.
2:30-2:45 > Coffee/Tea Break
2:45-3:15 > Predictive and scalable platform to test toxicity and efficacy of compounds directly on patients derived 3D neuromuscular junction-on-a-chip
Margaret Magdesian, PhD,Ananda Devices
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[ 3:15-4:15 ]
Poster Session
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[ 4:15-4:30 ]
Break
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[ 4:30 – 6:00 pm ]
Trainee-Focussed Session
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[ 4:30 – 6:00 pm ]
STC Annual Business Meeting
All STC Members
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[ 6:30 pm ]
Reception & Awards
All attendees are welcome
Finger foods & refreshments provided and cash bar
DAY 3 – December 5
[ 8:30 – 10:00 am ]
SESSION III
Safety biomarkers in translation toxicology
Chair – TBD | Co-chair – Richard Bagshaw, PhD, Nucro-Technics
8:30-9:00 > Next-Gen Genotoxicity Testing: where Genomics and Transcriptomics Meet
Carole Yauk, PhD, Department of Biology, University of Ottawa
9:00-9:30 > Implementation of translational safety biomarkers following health authority qualification
Nicholas King, PhD, Executive Director Predictive Safety Testing Consortium, Critical Path Institute
9:30-10:00 > ICH 1 Addendum – Alternative Approaches for Carcinogenicity Testing of Pharmaceuticals
Alisa Vespa, PhD, Senior Scientific Evaluator, Health Canada
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[ 10:00 – 10:15 am ]
Coffee/Tea Break
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[ 10:15 – 11:00 am ]
Barbara Hales Award Lecture
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[ 11:15 – 12:00 am ]
Gabriel L Plaa Award Lecture
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[ 12:00 am – 1:00 pm ]
Lunch
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[ 1:00- 1:45 pm ]
Henderson Award Lecture
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[ 1:45 – 2:15 pm ]
Short Oral Presentations
Selected Abstracts
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[ 2:15 – 4:00 pm ]
SESSION IV
Food Chemical Safety: Science & Regulation
Chair – Samuel Godefroy, PhD, Laval University | Co-chair – Anne Marie Gannon, PhD, Health Canada
2:15-3:00 > The State of Science of TiO2 as a Food Additive
Catherine Smith and Gordon Barrett, Health Canada
3:00-3:15 > Coffee/Tea Break
2:15-2:35 > Cellular Agriculture Products
David Prescott, PhD Health Canada
2:35-2:55 > Global Harmonizing of Food Safety Regulations
Samuel Godefroy, PhD, Laval University
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[ 4:00 – 4:15 pm ]
Closing Remarks
DEADLINES
- Registration: Early-Bird October 31st / Final November 26th
- Abstracts: October 16th
- Hotel room bookings: November 4th
PAYMENT FEES
Early-Bird (before October 31st)
In-Person
- Regular Member $500 / Non-Member $800
- Postdoc Member $300 / Postdoc Non-member $400
- Grad Student Member $200 / Grad Student Non-member $300
Virtual
- Member $400 / Non-Member $700
- Postdoc Member $200 / Postdoc Non-member $300
- Grad Student Member $100 / Grad Student Non-member $200
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Regular
In-Person
- Member $600 / Non-Member $900
- Postdoc Member $400/ Postdoc Non-member $500
- Grad Student Member $300 / Grad Student Non-member $400
Regular Virtual
- Member $500 / Non-Member $800
- Postdoc Member $300 / Postdoc Non-member $400
- Grad Student Member $200 / Grad Student Non-member $300
Please note there will not be any on-site registration, taxes to be added based on the province where the symposium is held
PLENARY LECTURE
Monday, December 4, 10:30-11:30 AM
From Toxicity Testing for the 21st Century to a Human Exposome Project
Thomas Hartung, MD PhD
Johns Hopkins University, USA
Thomas Hartung, MD PhD, is the Doerenkamp-Zbinden-Chair for Evidence-based Toxicology in the Department of Environmental Health and Engineering at Johns Hopkins Bloomberg School of Public Health and the Whiting School of Engineering, Baltimore. He also holds a joint appointment for Molecular Microbiology and Immunology at the Bloomberg School. He is adjunct affiliate professor at Georgetown University, Washington D.C.. In addition, he holds a joint appointment as Professor for Pharmacology and Toxicology at University of Konstanz, Germany; he also is Director of Centers for Alternatives to Animal Testing (CAAT, http://caat.jhsph.edu) of both universities. CAAT hosts the secretariat of the Evidence-based Toxicology Collaboration (http://www.ebtox.org) and manages collaborative programs on Good Read-Across Practice, Good Cell Culture Practice, Green Toxicology, Developmental Neurotoxicity, Developmental Immunotoxicity, Microphysiological Systems and Refinement. As PI, he headed the Human Toxome project funded as an NIH Transformative Research Grant and the series of annual Microphysiological Systems World Summits starting in 2022 by 60+ organizations. He is Field Chief Editor of Frontiers in Artificial Intelligence. He is the former Head of the European Commission’s Center for the Validation of Alternative Methods (ECVAM), Ispra, Italy, and has authored more than 630 scientific publications with more than 43,000 citations (h-index 109). His toxicology classes on COURSERA had almost 17,000 active learners.
VENUE – Double tree Hilton, Montreal
Deadline for STC Special group pricing – November 3rd – FIRM
Room reservations can also be made over the phone by calling 1-800-361-8234.
Guests should mention the name of your event: Society of Toxicology
Visit Montreal
Arrive ahead of the meeting or stay after and enjoy all downtown Montreal has to offer. Visit Tourism Montreal
